XIX. Symposium der GTFCh, 16. - 18. April 2015 in Mosbach
GTFCh Bilder zu der Veranstaltung (Link auf Cloud-Storage)
Tagungspräsident: Prof. Dr. Volker Auwärter
Institut für Rechtsmedizin, Universitätsklinikum Freiburg
Wissenschaftliches Komitee: Georg Schmitt, Gisela Skopp
Institut für Rechtsmedizin und Verkehrsmedizin, Universitätsklinikum Heidelberg
Tagungszentrum: Alte Mälzerei, Alte Bergsteige 7, Mosbach (Baden), e-mail: Diese E-Mail-Adresse ist vor Spambots geschützt! Zur Anzeige muss JavaScript eingeschaltet sein.
Mittwoch, 15. April 2015
20:00 Uhr Mittwochsvortrag für die Mosbacher Öffentlichkeit
„Wenn`s rummst - Tatortbearbeitung bei Sprengstoffexplosionen“
Dr. Klaus Stein, Bayerisches Landeskriminalamt, München
Donnerstag, 16. April 2015
Satellitensymposium
- für angemeldete Teilnehmer -
Soll Cannabis verboten bleiben? Ein wissenschaftlicher Diskurs.
14:00 Uhr Eröffnung und Begrüßung / Opening and welcome
Dr. Franjo Grotenhermen (Arzt, Rüthen)
Medizinischer Nutzen von Cannabis
Prof. Dr. Rainer Thomasius (Universitätsklinikum Hamburg-Eppendorf, Hamburg)
Cannabis – eine unterschätzte Gefahr für die Jugend?
Prof. Dr. Wolfgang Schubert (Präsident der Deutschen Gesellschaft für Verkehrspsychologie (DGVP))
Cannabis und Fahreignung: Steigerung der Verkehrssicherheit oder Sanktionen durch die Hintertür?
Sebastian Glathe (Rechtsanwalt, Freiburg)
Cannabis und Strafrecht: Unerwünschte Effekte der Cannabisprohibition
Dr. Bernd Werse (Centre for Drug Research, Goethe-Universität, Frankfurt am Main)
Prävalenz und gesetzlicher Status von Cannabis – ein europäischer Vergleich
Podiumsdiskussion
Pro und Contra Cannabislegalisierung (Teilnehmer: die Referenten, Frank Tempel (MdB), Jörn Patzak (OStA), Moderation: Prof. Dr. Volker Auwärter)
18:00 Uhr Sitzungsende / End of session
20:00 Uhr Abendveranstaltung / Evening event
Empfang durch Herrn Bürgermeister Michael Keilbach
im Gemeindesaal des kath. Pfarramtes St. Cäcilia, Franz-Roser-Platz 2, 74821 Mosbach
Freitag, den 17. April 2015
Symposium
09:00 Uhr Eröffnung des Symposiums und Grußworte / Opening of the symposium and welcome speeches
09:10 Uhr Vorträge: Neues aus der Kriminaltechnik, Trends / Oral presentations: News from forensic science, trends
V01 Harald John, Felix Gandor, Michael Gawlik, Andreas Kranawetvog1, Horst Thiermann, München, Berlin, Hamm
An albumin adduct with the chemical warfare agent sulfur mustard detected by LC-ESI MS/MS: a novel method for verification of poisoning
V02 Susanne Vogt, Martina Hauschel, Verena Angerer, Jürgen Kempf, Volker Auwärter, Freiburg
Analysis of ‘poppers‘ products and analytical detectability of a single use of ‘poppers‘
V03 Jan Schäper, Marc Wende, München
“Shake and Bake” synthesis of methamphetamine – an experimental study
V04 Christian Bissig, Zürich (Schweiz)
Practical aspects of designer drug identification by means of solid phase GC-IR
V05 Lars Müller, Volker Auwärter, Verena Angerer, Michael Pütz, Laura M. Huppertz, Wiesbaden, Freiburg
A novel single-run-approach to detect, identify and quantitate synthetic cannabinoids in seized material using UHPLC-UV/DAD-MSn
V06 Verena Angerer, Volker Auwärter, Freiburg,
Monitoring of ‘legal high’ products 2013 and 2014
V07 Sára Harkai, Michael Pütz, Münster, Wiesbaden
Comparison of rapid detecting optical techniques for the identification of new psychoactive substances in ’Legal High’ preparations
V08 Volker Auwärter, Florian Franz, Verena Angerer, Bela Szabo, Maren Hermanns-Clausen, Siegfried Knasmüller, Ilkka Ojanperä, Bernd Werse, Karsten Tögel-Lins, Krystallia Karachaliou, Michael Pütz, Renate Lind-Krämer, Teemu Gunnar, Lars Ambach, Wolfgang Weinmann, Freiburg, Wien (Österreich), Helsinki (Finnland), Frankfurt am Main, München, Wiesbaden, Bern (Schweiz)
The EU project ‘SPICE II Plus’: Summary of the key findings
V09 Michael Pütz, Volker Auwärter, Sascha Münster-Müller, Sabine Schneiders, Wiesbaden, Freiburg
The EU-project ´SPICE-profiling´ (2015-2017) - objectives and results of a pre-study
11:00 Uhr Kaffeepause / Coffee break
11:30 Uhr Vorträge: Neues aus der Kriminaltechnik, hochauflösende Massenspektrometrie / Oral presentations: News from forensic science, high-resolution mass spectrometry
V10 Laura M. Huppertz, Philippe Bisel, Folker Westphal, Florian Franz, Volker Auwärter, Bjoern Moosmann, Freiburg, Kiel
Characterisation and in-vitro metabolite identification of the four new designer benzodiazepines clonazolam, deschloroetizolam, flubromazolam and meclonazepam
V11 Julian A. Michely, Julia Dinger, Simon D. Brandt, Markus R. Meyer, Hans H. Maurer, Homburg (Saar), Liverpool (England)
N,N-Diallyltryptamine (DALT) designer drugs: Metabolism, CYP inhibition potential, and urinary detectability of five typical representatives using GC-MS, LC-MSn, and LC-HR-MS/MS techniques
V12 Achim T. Caspar, Andreas G. Helfer, Volker Auwärter, Simon D. Brandt, Markus R. Meyer, Hans H. Maurer, Homburg (Saar), Freiburg, Liverpool (England)
25I-NBOMe: Metabolism and detectability of a novel synthetic hallucinogen - studied by GC-MS, LC-MSn, and LC-HR-MS/MS
V13 Andreas G. Helfer, Julian A. Michely, Armin A. Weber, Markus R. Meyer, Hans H. Maurer, Homburg (Saar)
LC-HR-MS/MS standard urine screening approach: Comparison of urine dilution, precipitation, or TurboFlow online extraction exemplified for 20 cardiovascular drugs
V14 Sabrina Lehmann, Tobias Kieliba, Justus Beike, Markus A. Rothschild, Katja Mercer-Chalmers-Bender, Köln
Rapid determination of new psychoactive substances in biological matrices using an automated ITSP™ solid-phase extraction and LC-MS/MS
12:30 Uhr Mittagspause / Lunch break
13:15 Uhr Posterausstellung mit Kaffeetheke / Poster session and coffee bar
P01 Frank Sporkert, Thomas Daldrup, Ulrich Demme, Marek Dziadosz, Freidoon Erdmann, Cornelia Franzelius, Stefanie Hammer, Gertrud Rochholz, Thomas Stimpfl, Jörg Teske, Michaela Winkler, Lausanne (Schweiz), Düsseldorf, Jena, Hannover, Giessen, Kiel, Dortmund, Wien (Österreich), Ulm
Extraction of further toxicologically relevant compounds with 1-chlorobutane – a systematic investigation
P02 Verena Angerer, Fabian Süßenbach, Nina Hirschinger, Volker Auwärter, Freiburg
Validated LC-MS/MS method for qualitative and quantitative analysis of 75 synthetic cannabinoids in serum
P03 Florian Franz, Georg Weinfurtner, Nadja Schwörer, Volker Auwärter, Freiburg, Regensburg
Immunoassay screening in urine for synthetic cannabinoids – a feasible approach for forensic applications?
P04 Sarah Schumacher, Harald Seitz, Potsdam
Multiplex approach for an immunological detection of drug abuse: A validation study
P05 Katharina M. Köhler, Raija Hammer, Kathrin Riedy, Volker Auwärter, Merja A. Neukamm, Freiburg
Validation of CEDIA® and DRI® drugs of abuse immunoassays for urine screening on a Thermo Scientific Indiko Plus analyser
P06 Amanda Leffler, Bernd Thierfelder, Seyed Sadjadi, Shahana Huq, Sean Orlowicz, Kalifornien (USA), Aschaffenburg
A comprehensive screening of illicit and pain management drugs from whole blood matrix using SPE and LC/MS/MS
P07 Julian A. Michely, Andreas G. Helfer, Markus R. Meyer, Hans H. Maurer, Homburg (Saar)
Is LC-high-resolution-MS/MS a suitable alternative to ELISA in diagnosis of Amanita phalloides poisonings? - A two years’ experience
P08 Marianne Hädener, Wolfgang Weinmann, Stefan König, Bern (Schweiz)
Rapid extraction of THC-COOH and THC-COO-glucuronide from human urine and quantitative analysis by column-switching LC-MS/MS
P09 Patrick C. Dolder, Evangelina Liakoni, Matthias E. Liechti, Katharina M. Rentsch, Basel (Schweiz)
Identification of recreational drugs in patients admitted to the emergency department – a retrospective analysis
P10 Marcel Grapp, Herbert Desel, Göttingen
Systematic forensic toxicological screening by GC-MS in serum using automated mass spectral deconvolution and identification system
P11 Susanne Nussbaumer, Thomas Wüthrich, Wolfgang Weinmann, Stefan König, Bern (Schweiz)
Metabolite profiling by SWATH acquisition: application to forensic samples
P12 Helena Fels, Torsten Dame, Hans Sachs, Frank Musshoff, München
Development, validation and application of a qualitative LC-QTOF-MS screening method for post-mortem urine samples
P13 Jürgen Kempf, Christine Stronczek, Laura M. Huppertz, Susanne Vogt, Freiburg
Automated ion trap LC-MS screening for xenobiotics in vitreous humor
P14 Eberhard Scheuch, Sven-Olaf Kuhn, Ulrich Hoffmann, Greifswald
Prolonged half-life of some central depressant drugs in brain death
P15 Konrad Sydow, Burkhard Madea, Frank Musshoff, Cornelius Hess, Bonn
Evaluation of post mortem amino acid concentrations in vitreous humor with known post-mortem intervals
P16 Gernot Brauers, Tanja Hammen, Irina Steiner, Thomas Daldrup, Düsseldorf
Kidney juice, an alternative matrix for the forensic toxicology
P17 Evelyn Pawlik, Hellmut Mahler, Benno Hartung, Gerd Plässer, Thomas Daldrup, Düsseldorf
Analysis of adulterants from cocaine preparations in lung tissue and blood
P18 Julia Krüger, Matthias Graw, Frank Musshoff, Hans Sachs, Gabriele Roider, München
Analysis of propofol, midazolam and atracurium in dried spots on a carpet
P19 Patrick C. Dolder, Matthias E. Liechti, Katharina M. Rentsch, Basel (Schweiz)
Quantification of LSD and 2-oxo-3-hydroxy LSD in serum and urine samples of five acute emergency toxicological cases
P20 Helena Fels, Julia Krueger, Andreas Stoever, Torsten Dame, Hans Sachs, Gabriele Roider, Frank Musshoff, München
Fatal intoxication after consumption of a high dose of the synthetic opioid AH-7921
P21 Christina Grumann, Maren Hermanns-Clausen, Josephine Kithinji, Verena Angerer, Volker Auwärter, Freiburg
Accidental intoxication with 25I-NBOMe
P22 Patricia Anielski, Bernd Schwarze, Detlef Thieme, Kreischa, Erlangen
Detection of the abortifacient mifepristone (Mifegyne, RU-486) in a hair sample after illegal administration
P23 Sonja Heinl, Freidoon Erdmann, Oliver Lerch, Gießen, Mülheim an der Ruhr
Comprehensive automation of the determination of THC, CBN and CBD in hair by GC/MS
P24 Silvana Witt, Stefan W. Toennes, Frankfurt (Main)
A rapid method for the detection of oxidative hair treatment using fluorescence microscopy
P25 Alexander Müller, Stefanie Iwersen-Bergmann, Hilke Jungen, Lars Radünz, Hilke Andresen-Streichert, Hamburg
Analysis of ethyl glucuronide in human hair samples: A multivariate analysis of the impact of extraction conditions on quantitative results
P26 Luc Kirchen, Michel Yegles, Juergen Schram, Dudelange (Luxemburg), Krefeld6
Are new psychoactive drugs missed in routine forensic analysis of serum and hair?
P27 Barbara Hinterberger, Bernd Bodiselitsch, Balazs Horvath, Olaf Nehlich, Thomas Stimpfl, Wien, Neutal (Österreich)
Extending the detection window for GHB in urine using isotope-ratio mass spectrometry
P28 Nadja Schwörer, Verena Angerer, Laura M. Huppertz, Florian Franz, Volker Auwärter, Freiburg
Metabolism and urine analysis of the new synthetic cannabinoid MDMB-CHMICA
P29 Cornelius Hess, Clara Schoeder, Christa E. Müller, Burkhard Madea, Bonn
CB1 and CB2 receptor affinities of synthetic cannabinoids sold on the illicit drug market
P30 Marie Martin Fabritius, Wolfgang Weinmann, Marc Augsburger, Christian Giroud, Lausanne, Bern (Schweiz)
THCCOOH concentrations in whole blood: a useful tool to discriminate occasional from heavy smokers
P31 Carsten Bartling, Michael Böttcher, Köln, Dessau
Stability studies on ethyl glucuronide (EtG) in bacterially contaminated urines
P32 Michael Böttcher, David Kühne, Dessau
False-positive ethyl glucuronide immunoassay after anaesthesia with sevoflurane
P33 Monika Jokiel, Gisela Skopp, Heidelberg
N-Acetyltaurine – preliminary work to prove its potential as a marker of alcohol consumption
P34 Andreas Längin, Sebastian Wegerer, Werner Bernhard, Wolfgang Weinmann, Bern (Schweiz), Müllheim
Implementation of HS-GC-FID blood alcohol determination and data validation by a LIMS according to Swiss regulations
P35 Georg Schmitt, Gisela Skopp, Heidelberg
Control charts for internal quality control in forensic-toxicological analyses
P36 Alexandra Schröck, Annette Thierauf-Emberger, Wolfgang Weinmann, Bern (Schweiz), Freiburg
Phosphatidylethanol (PEth) detectable in blood for 3 to 12 days after single consumption of alcohol – a drinking study with 16 volunteers
P37 Michael Krämer, Pai-Shan Chen, Konrad Sydow, Burkhard Madea, Cornelius Hess, Bonn, Taipei (Taiwan)
ATM4G – an additional marker for the intake of German street heroine
Kaffeepause / Coffee break
14:15 Uhr Vorträge: Toxikokinetik / Oral presentations: Toxicokinetics
V15 Nadine Schaefer, Mattias Kettner, Matthias W. Laschke, Julia Schlote, Benjamin Peters, Dietmar Bregel, Michael D. Menger, Hans H. Maurer, Andreas H. Ewald, Peter H. Schmidt, Homburg (Saar)
Disposition of JWH-210, RCS-4, THC, and their main metabolites in pig serum and whole blood following intravenous administration - a pilot study
V16 Andrea E. Steuer, Corina Schmidhauser, Yasmin Schmid, Anna Rickli, Matthias E. Liechti, Thomas Kraemer, Zürich, Basel (Schweiz)
Pharmacokinetic blood plasma analysis of MDMA and its phase I and phase II metabolites after controlled MDMA administration to humans
V17 Julia Dinger, Julian A. Michely, Markus R. Meyer, Hans H. Maurer, Homburg (Saar)
In vitro cytochrome P450 (CYP) inhibition potential of 12 tryptamine-derived designer drugs elucidated by a novel cocktail inhibition assay
V18 Stefanie Iwersen-Bergmann, Alexander Müller, Hilke Andresen, Hilke Jungen, Lars Radünz, Herbert Oberacher, Beate Beer, Hamburg, Innsbruck (Österreich)
Brain/blood ratios of methadone in methadone related deaths and ABCB1 polymorphisms
V19 Markus R. Meyer, Lea Wagmann, Nicole Schneider-Daum, Brigitta Loretz, Cristiane de Souza Carvalho, Claus-Michael Lehr, Hans H. Maurer, Homburg (Saar), Saarbrücken
P-glycoprotein interactions of novel psychoactive substances - stimulation of ATP consumption and transport across Caco-2 monolayers
V20 Florian Franz, Nadja Schwörer, Verena Angerer, Laura M. Huppertz, Bjoern Moosmann, Volker Auwärter, Freiburg
Metabolism of synthetic cannabinoids – similarities and differences between metabolic patterns of different structural subclasses
V21 Nicole Stachel, Gisela Skopp, Heidelberg
In vitro formation of ethyl glucuronide and ethyl sulfate
15:30 - 17:30 Uhr Mitgliederversammlung / Business Meeting
19:00 Uhr Festabend mit Verleihung des Jean-Servais-Stas-Preises und des Nachwuchspreises für Wissenschaftlerinnen und Wissenschaftler
Congress ceremony and dinner – Presentation of the 2015 laureate of the Jean-Servais-Stas award and of the winner of the GTFCh Young Scientists award
Congress ceremony and dinner – Presentation of the 2015 laureate of the Jean-Servais-Stas award and of the winner of the GTFCh Young Scientists award
Festvortrag / Lecture
Prof. Dr. med. Burkhard Madea (Bonn): Der Fall Rohrbach
23:00 Uhr After Dinner Party (Hopfenkeller der Alten Mälzerei)
Samstag, 18. April 2015
9:00 Uhr Vorträge: Alternative Matrices, Kasuistiken / Oral presentations: Alternative matrices, case reports
V22 Miriam Klima, Laura M. Huppertz, Markus J. Altenburger, Volker Auwärter, Merja A. Neukamm, Freiburg
In vitro studies on the incorporation of medical and illicit drugs into dental hard tissue
V23 Merja A. Neukamm, Miriam Klima, Laura M. Huppertz, Markus J. Altenburger, Volker Auwärter, Andreas Reinecke, Simone Krais, Freiburg, Berlin
Analysis of prehistorical dental hard material for betel nut alkaloids by liquid chromatography-mass spectrometry (LC-MS/MS and LC-HR-TOF-MS)
V24 Tina M. Binz, Mona Bosshard, Markus R. Baumgartner, Thomas Kraemer, Zürich (Schweiz)
Development and validation of an LC-MS/MS method for the quantification of cortisol in hair
V25 Thomas Franz, Detlef Thieme, Gerlinde Schwarz, Hans Sachs, Frank Musshoff, Rheinbach, München, Kreischa
Evaluation of active cannabis consumption via testing of the THC-metabolites 11-hydroxy-THC and 11-nor-carboxy-THC
V26 Bjoern Moosmann, Volker Auwärter, Freiburg
Δ9-Tetrahydrocannabinol (THC) and 11-nor-9-carboxy-THC (THC-COOH) findings in hair samples after controlled oral intake of dronabinol
V27 Sandra N. Staeheli, Andrea E. Steuer, Michael Poetzsch, Thomas Kraemer, Zürich (Schweiz)
Validation of an LC-MS/MS quantification method for 85 substances in 8 postmortem matrices
V28 Fritz Pragst, Bernd Kopetz, Sieglinde Herre, Berlin, Bad Saarow
Accidental death by toxic lung edema in a cyclone for waste gas cleaning of an industrial heating station – a case report
V29 Sarah Hangartner, Jasmin Steiner, Franz Dussy, Regula Möckli, Kathrin Gerlach, Thomas Briellmann, Basel (Schweiz)
A pet’s death
V30 Wiebke Rudolph, Daniela Remane, Björn Moosmann, Sebastian Lemke, Volker Auwärter, Frank T. Peters, Jena, Freiburg
First reported intoxication involving the four designer benzodiazepines, flubromazepam, diclazepam, pyrazolam, and etizolam
10:40 Uhr Kaffee-Pause / Coffee Break
11:10 Uhr Vorträge: Freie Themen aus der Forensischen Chemie und Toxikologie / Oral presentations: communications in forensic chemistry and toxicology
V31 Alexander Paulke, Christian Kremer, Cora Wunder, Stefan W. Toennes, Frankfurt (Main)
Follow up on a new old natural high: Lysergic acid amide (LSA) containing seeds of Argyreia nervosa
V32 Alexandra Schröck, Peter Bütikofer, Wolfgang Weinmann, Bern (Schweiz)
Development of a standardised test for the activity of phospholipase D (PLD) responsible for biosynthesis of phosphatidylethanol (PEth)
V33 Stephanie Hanisch, Werner Pogoda, Alexander Paulke, Stefan W. Toennes, Frankfurt (Main)
Investigations on the nature of a recently detected THCCOOH isomer: incubation experiments
V34 Lena-Maria Mehling, Alexandra Maas, Burkhard Madea, Frank Mußhoff, Annika Spottke, Cornelius Heß, Bonn
GHB-O-β-D-glucuronide – determination of endogenous concentrations in plasma and urine samples and estimation of a clinical trial
V35 Susanne Lott, Thomas Piper, Lena-Maria Mehling, Annika Spottke, Alexandra Maas, Mario Thevis, Burkhard Madea, Cornelius Hess, Bonn, Köln
Measurement of exogenous gamma-hydroxybutyric acid (GHB) in urine using isotopic ratio mass spectrometry (IRMS)
V36 Andreas T. Roemmelt, Andrea E. Steuer, Thomas Kraemer, Zürich (Schweiz)
Demultiplexing, deconvolution or variable Q1 windows? Best approach to enhance specificity of SWATH generated MS2 spectra
V37 Jennifer Schürenkamp, Angela Gasse, Heidi Pfeiffer, Helga Köhler, Münster
Difficulties arising from new blood collection tubes for ethanol determination
V38 Golo M. J. Meyer, Jochen Beyer, St. Gallen (Schweiz)
Fast and simple microwave assisted work-up procedure for urine analysis by GC-MS
12:50 Uhr Schlusswort zum Symposium / Closing words
13:00 Uhr Tagungsende / End of the meeting