XXI. Symposium der GTFCh, 11. - 13. April 2019 in Mosbach

 GTFCh  Programm (Download des Programms im PDF-Format)

Tagungspräsident: Volker Auwärter
Institut für Rechtsmedizin, Universitätsklinikum, Freiburg

Wissenschaftliches Komitee: Gisela Skopp, München

Tagungszentrum: Alte Mälzerei, Alte Bergsteige 7, Mosbach (Baden), e-mail: Diese E-Mail-Adresse ist vor Spambots geschützt! Zur Anzeige muss JavaScript eingeschaltet sein!

 

Mittwoch, 10. April 2019

20:00 Uhr     Mittwochsvortrag für die Mosbacher Öffentlichkeit

„CSI in Mosbach!?-Forensische Toxikologie nicht so wie im Fernsehen“
PD. Dr. Hilke Andresen-Streichert, Institut für Rechtsmedizin, Köln

 

Donnerstag, 11. April 2019

11:30 Uhr    Stadtführung

Treffpunkt und Kofferbunker: Tourist Information am Marktplatz (ca. 3 Minuten vom Bahnhof Mosbach (Baden) entfernt)
Ende der Führung: 12:45 Uhr an der Tourist Information
 

12:00 Uhr    Young Scientifics-Treffen /Meeting of young scientitst

Treffen der Doktoranden/innen und jungen Wissenschaftler/innen in der Alten Mälzerei, Ende: 13:30 Uhr
NpSG (Neue-psychoaktive-Stoffe-Gesetz)
 

Satellitensymposium

Bedeutung der forensischen Toxikologie und Chemie in der juristischen, medizinischen und psychologischen Praxis

14:00 Uhr     Eröffnung und Begrüßung / Opening and welcome

Prof. Dr. med. Torsten Passie (Dr. Senckenbergisches Institut für Geschichte und Ethik der Medizin, Goethe-Universität, Frankfurt)
LSD, Psilocybin und MDMA: Therapeutische Anwendung und aktuelle Therapiestudien

Prof. Dr. med Kirsten Müller-Vahl (Klinik für Psychiatrie, Sozialpsychiatrie und Psychotherapie, Medizinische Hochschule, Hannover
Cannabis als Medizin: Fakten zu Anwendung und Wirkung

Prof. Dr. Matthias Karst (Klinik für Anästhesiologie und Intensivmedizin, Leiter der Schmerzambulanz, Medizinische Hochschule, Hannover)
Opioide Dr. Jekyll and Mr. Hyde

Prof. Dr. Med. Malek Bajbouj (Klinik für Psychiatrie und Psychotherapie (CBF), Leiter Bereich Affektive NEurowissenschaften, Charite - Universitätsmedizin Berlin 
Ketamin in der Depressionsbehandlung - Chancen und Risiken

 

18:00 Uhr     Sitzungsende / End of session
 

19:15 Uhr    Orgelabend, Stiftskirche am Rathaus / Organ night, Stiftskirche am Rathaus
Dr. Jan Schäper (Bayerisches Landeskriminalamt, München)

20:00 Uhr     Abendveranstaltung / Welcome reception
Empfang durch Herrn Bürgermeister Rathaus Mosbach

 
 


 
Freitag, 12. April 2019

Symposium


09:00 Uhr     Eröffnung des Symposiums und Grußworte / Opening of the symposium and welcome speeches

09:10 Uhr        Vorträge: Alternative Matrices / Oral presentations: Alternative matrices

V01    Thomas Grobosch, Paul Kuhlich, Silke Cox, Berlin, Wiesbaden
The planned brutal murder of the pregnant woman Maria P.

V02    Daniela Remane, Julia Dinger, Sylvia Morgenthal, Christin König, Gita Mall, Frank T. Peters, Jena
A "recipe" to suicide - Fatal poisoning with chloroquine

V03    Lana Brockbals, Sandra N. Staeheli, Simon Gentile, Markus Schlaepfer, Christian Bissig, Stephan A. Bolliger, Thomas Kraemer, Andrea E. Steuer, Zürich (Schweiz)
Fatal poisoning involving cyclopropylfentanyl - Investigation of time-dependent post-mortem redistriubtion

V04    Roelof Oosting, Lauriane Drouin, Rogier Van der Hulst, Ingrid Bosman, Den Haag (Niederlande) 
A fatal intoxication with 4-fluoroisobutyrylfentanyl

V05    Sabrina Lehmann, Alissa Sczyslo, Judith Froch-Cortis, Markus A. Rothschild, Mario Thevis, Hilke Andresen-Streichert, Katja Mercer-Chalmers-Bender, Köln, Basel (Schweiz)
Organ distribution of diclazepam, pyrazolam and 3-fluorophenmetrazin

V06    Sabrina Lehmann, Andreas Tomas, Karl-Heinz Schiwy-Bochat, Hans Geyer, Mario Thevis, Frank Glenewinkel, Markus A. Rothschild, Hilke Andresen-Streichert, Martin Juebner, Köln
Death after misuse of anabolic substances (clenbuterol, stanozolol and metandienone)

V07    Vanessa Hofmann, Aysche Landmann, Georg Schmitt, Marc Bartel, Heidelberg, 
Analytical separation of 5- and 6-APB and their distribution in the human body

V08    Lea Wagmann, Sascha K. Manier, Hans H. Maurer, Markus R. Meyer, Homburg (Saar)
Polytoxicomania involving four synthetic cathinones: a case report and subsequent toxicokinetic studies

V09    Gertrud Rochholz, Saskia Jung, Magdalena Eckner, Kiel
Nicotine used as a date rape drug


11:00 Uhr     Kaffeepause / Coffee break
 
11:30 Uhr     Vorträge: Neues aus der Kriminaltechnik / Oral presentations: News from forensic science

V10    Svenja Fischmann, Volker Westphal, Kiel
The EU-project ADEBAR for substance identification, analytical data provision and reference material

V11    Jan Schäper, München
Illicit production of herbal blends and actual trends on the NPS-market

V12    Sonja Metternich, Siegfried Zörntlein, Torsten Schönberger, Carolin Huhn, Mainz
Ion mobility spectrometry as a fast screening tool for synthetic cannabinoids to uncover drug trafficking in jail via herbal mixtures, papers, food and cosmetics

V13    Fabian Stahlkopf, Voker Westphal, Kiel
Quantitative estimation of cocaine and amphetamine in seized mixtures using Raman spectroscopy

V14    Marianne Hädener, Tim J. Gelmi, Marie Martin-Fabritius, Wolfgang Weinmann, Matthias Pfäffli, Bern (Schweiz)
Cannabinoid concentrations in confiscated cannabis samples and in whole blood and urine after smoking CBD-rich cannabis as a "tabacco" substitute


12:30 Uhr     Mittagspause / Lunch break


13:15 Uhr     Posterausstellung mit Kaffeetheke / Poster session and coffee bar

P01    Michaela Sommer, Sebastian Halter, Verena Angerer, Volker Auwärter, Maren Hermanns-Clausen, Freiburg, St. Gallen (Schweiz)
Impact of the NpSG on the number of hospitalisations due to NPS use

P02        Aurore Wicht, Volker Auwärter, Jürgen Kempf, Freiburg
Identification and quantitative determination of active ingredients in drug exhibits by LC-MSn

P03    Imke Stamme, Nathalie Martin, Carolin Huhn, Michael Pütz, Tübingen, Wiesbaden
Application of CE-DAD for the identification of food colorants in illicit drugs with complex matrices

P04    Bianca Schaffrath, Folker Westphal, Kiel 
Establishment of a new GC-FID method for the quantitative determination of cathinone-type designer drugs using cross-calibration calculations

P05    Marc Luginbühl, Wolfgang Weinmann, Ali Al-Ahmad, Bern (Schweiz), Freiburg
Introduction of sample tubes with sodium azide as a preservative for ethyl glucuronide in urine    

P06        Merja A. Neukamm, Arsham Bahrami, Volker Auwärter, Felix M. P. Mehne, Eva Höss, Freiburg, Penzberg
Forensic abstinence control with KIMS immunoassays for drugs of abuse and ethyl glucuronide in urine on a cobas c 501 analyzer

P07    Marie Martin Fabritius, Helene Urbain, Rolf Aderjan, Wolfgang Weinmann, Bern (Schweiz), Lörrach, Neckarsteinach
Detection of driving under the influence of cannabis or cocaine using P.I.A. lateral flow tests in plasma confirmed with LC-MS/MS or GC-MS    

P08    Alexandra Maas, Christoph Maier, Beate Michel-Lauter, Burkhard Madea, Cornelius Hess, Bonn, Bochum
1,2-Dimethylimidazole-4-sulfonyl chloride (DMISC), a novel derivatization strategy for the analysis of propofol by LC-ESI-MS/MS    

P09        Marek Dziadosz, Michael Klintschar, Jörg Teske, Hannover
The analysis of THC and its metabolites in human serum with LC-MS/MS on the basis of protein precipitation

P10        Michael Pötzsch, Roger Odermatt, Andreas T. Roemmelt, Andrea E. Steuer, Thomas Kraemer, Zürich (Schweiz)
Quantitation of cannabinoids in whole blood after protein precipitation – Online solid-phase extraction LC-ESI-MS/MS versus LC-APCI-MS/MS

P11        Shahana Wahab Huq, Sean Orlowicz, Guido Rimmel, Joseph Sullivan, Torrance (Kalifornien, USA), Aschaffenburg, San Jose (Kalifornien, USA)
Automated drugs of abuse analysis from oral fluid

P12        Wolfgang Dreiseitel, Rebecca Prasse, Wiesbaden, Aalen
Quantification and distribution of NBOMes on blotter sheets

P13        Alexandra Maas, Konrad Sydow, Burkhard Madea, Cornelius Hess, Bonn
Separation of ortho, meta and para isomers of methylmethcathinone (MMC) and methylethcathinone (MEC) using LC-ESI-MS/MS: Application to forensic serum samples

P14        Torsten Dame, Helena Fels, Hans Sachs, Frank Musshoff, München
LC-QTOF-MS peak pattern analysis to detect excessive consumption of nutmeg

P15    Előd Hidvégi, Klaudia Kemenes, Adrienn Dobos, Gábor P. Somogyi, Budapest (Hungary)
5F-MDMB-PICA as a marker of synthetic cannabinoid abuse: the use of methylation and GC/MS-analysis of the urine extracts of abusers

P16    Helena Fels, Torsten Dame, Hans Sachs, Frank Musshoff, München
Development and application of a qualitative LC-QTOF-MS screening method for the detection of bath salts in body fluids and hair samples    

P17    Katharina Grafinger, Lars Ambach, Florian Franz, Verena Angerer, Wolfgang Weinmann, Bern (Schweiz), Ghent (Belgien), Freiburg
Update of an MS/MS library of NPS for QTRAP® instruments

P18        Jürgen Kempf, Nadine Schiesel, Laura M. Huppertz, Rafaela Martin, Volker Auwärter, Freiburg, Bremen
Quantitation of 99 synthetic cannabinoids in serum by liquid chromatography-electrospray ionization tandem mass spectrometry

P19    Gerard Haak, Ruth Verplaetse, Jack Henion, Nina Meszaros, Emmen (Niederlande), Ithaca (New York, USA), Sprockhövel
Monitoring opioid use for pain management using a fully automated DBS-SPE-LC/MS/MS approach 

P20        Maurice Wilde, Verena Angerer, Bjoern Moosmann, Volker Auwaerter, Freiburg, St. Gallen (Schweiz)
Designer opioids – A new threat hitting the German drug market 

P21     Franziska Gaunitz, Sabrina Lehmann, Mario Thevis, Markus A. Rothschild, Katja Mercer-Chalmers-Bender
Fatal fall from a skyscraper following abuse of amphetamines, THC and the synthetic cannabinoid MDMB-CHMICA        

P22        Susanne Vogt, Christina Grumann, Annette Thierauf-Emberger, Volker Auwärter, Freiburg
Death by MDPHP

P23    Michael Krämer, Burkhard Madea, Cornelius Hess, Bonn
Postmortem redistribution of antipsychotic and antidepressive drugs    

P24    Alexander Müller, Stefanie Iwersen-Bergmann, Jan Sperhake, Hamburg
Analysis of the purple urine bag

P25    Marianne Knuth, Oliver Temme, Thomas Daldrup, Evelyn Pawlik, Düsseldorf
Analysis of cocaine adulterants in human brain of cases of drug-related death

P26    Marcel Grapp, Christian Vidal, Dieter Müller, Göttingen, Hannover
A case of acute intoxication with the designer drug α-pyrrolidinovalerophenone and its identification in human urine and blood by GC-MS        

P27        Christina Grumann, Susanne Vogt, Laura M. Huppertz, Bjoern Moosmann, Florian Franz, Verena Angerer, Lena Kramer, Volker Auwärter, Freiburg
A case of methoxphenidine intoxication

P28    Helena Fels, Frank Musshoff, Gabriele Roider, Matthias Graw, Stefanie Lottner-Nau, München
Eight fatalities involving the synthetic opioid U-47700    

P29        Marcel Grapp, Christoph Kaufmann, Martin Ebbecke, Göttingen
Intoxications related to the designer drug 3,4-methylenedioxypyrovalerone (MDPV) in the South of Lower Saxony: Detection, quantification and studies on human metabolism by GC-MS

P30    Nadine Strehmel, Elke Vejmelka, Kerstin Kastner, Sonja Roscher, Michael Tsokos, Stefan Scholtis, Berlin
NPS-findings in forensic toxicology – three case reports    

P31    Sabrina Lehmann, Franziska Gaunitz, Martin Jübner, Mario Thevis, Markus A. Rothschild, Katja Mercer-Chalmers-Bender, Köln
Prevalence of new psychoactive substances (NPS) at a popular annual festival in Cologne, Germany

P32    Sebastian Halter, Lukas Mogler, Verena Angerer, Volker Auwärter, Freiburg
The ‘NpSG’ (act to control the distribution of new psychoactive substances) – an effective weapon in the war on drugs?

P33    Lukas Mogler, Florian Franz, Verena Angerer, Bjoern Moosmann, Volker Auwärter, Freiburg
Phase I metabolism of the carbazole derivatives EG-018 and MDMB-CHMCZCA – A new class of synthetic cannabinoids circumventing the 'NpSG'    

P34        Maurice Wilde, Verena Angerer, Bjoern Moosmann, Volker Auwaerter, Freiburg, St. Gallen (Schweiz)
Phase I in vitro and in vivo metabolism of the designer opioid furanylfentanyl    

P35    Hilke Andresen-Streichert, Yannik Beres, Stefanie Iwersen-Bergmann, Alexandra Schröck, Wolfgang Weinmann, Gisela Skopp, Martina Sterneck, Alexander Müller, Köln, Hamburg, Bern (Schweiz), Heidelberg
The use of phosphatidylethanol (PEth) improved detection of alcohol consumption in pre- and post-liver transplantation patients

P36    David Kühne, Michael Böttcher, Dessau
Compliance testing of patients in ADHD treatment with Lisdexamfetamine using oral fluid samples

P37    Kerstin Henkel, Miriam Klima, Markus J. Altenburger, Miriam C. Kuales, Volker Auwärter, Merja A. Neukamm, Freiburg
Retention of illicit drugs in dental plaque - a model study regarding plaque as alternative matrix in forensic toxicology 

P38    Lina Gessner, Ursula Telgheder, Markus A. Rothschild, Katja Mercer-Chalmers-Bender, Martin Juebner, Köln, Essen
Evaluation of a simple quantification method for THC-COOH in dried blood spots

P39    Georg Schmitt, Gisela Skopp, Michael Herbold, Heidelberg, Walldorf
20 Years proficiency testing GTFCh

P40    Verena Angerer, Lukas Mogler, Jan-Patrick Steitz, Philippe Bisel, Cornelius Hess, Clara T. Schoeder, Christa E. Müller, Laura M. Huppertz, Folker Westphal, Jan Schäper, Volker Auwärter, Freiburg, Bonn, Kiel, München
Characterization of the new synthetic cannabinoid ‘Cumyl-PEGACLONE’ including first pharmacological data
 

Kaffeepause / Coffee break


14:15 Uhr     Vorträge: Toxikokinetik / Oral presentations: Toxicokinetics

V15    Nadine Schäfer, Daniel Moj, Thorsten Lehr, Andreas H. Ewald, Peter H. Schmidt, Frank Ramsthaler, Homburg/Saar, Saarbrücken
Pharmacokinetic modelling in a fatality following high morphine doses in palliative care

V16    Sascha K. Manier, Jan Schäper, Hans H. Maurer, Markus R. Meyer, Homburg/Saar, München
Studies on the in vitro metabolism of α-cathinones using pooled human liver microsomes and recombinant human CYP enzymes 

V17    Lilian H. J. Richter, Veit Flockerzi, Hans H. Maurer, Markus R. Meyer, Homburg/Saar
New psychoactive substances: Comparison of metabolites found in human liver preparations, human cell lines, and human urine - Exemplified for methylenedioxy derivatives and bioisosteric analogues 

V18    Anna Geraths, Werner Pogoda, Eef L. Theunissen, Jan G. Ramaekers, Stefan W. Toennes, Frankfurt/Main, Maastricht (Niederlande)
Pharmacokinetics of JWH-018 and its metabolites in serum

V19    Lea Wagmann, Tobias Kehl, Simon D. Brandt, Hans H. Maurer, Markus R. Meyer, Homburg/Saar, Liverpool (Großbritannien)
New psychoactive substances: In vitro metabolism of four LSD derivatives studied by means of LC-HR-MS/MS

V20    Lukas Mogler, Florian Franz, Verena Angerer, Georg Weinfurtner, Daniel Rentsch, Bjoern Moosmann, Volker Auwärter, Freiburg, Regensburg, Rostock
Detection of the novel synthetic cannabinoid 5F-MDMB-PICA in  human urine samples

V21    Achim T. Caspar, Jonas Gaab, Julian A. Michely, Simon D. Brandt, Markus R. Meyer, Hans H. Maurer, Homburg/Saar, Liverpool (Großbritannien)    
Metabolism and detectability of the new psychoactive substances 5-MeO-2-Me-DALT, 5-MeO-2-Me-ALCHT, and 5-MeO-2-Me-DIPT studied by GC-MS, LC-MSn, and LC-HR-MS/MS


15:45 Uhr     Mitgliederversammlung / Business meeting

17:30 Uhr     Ende der Mitgliederversammlung / End of the business meeting
 

19:00 Uhr    Festabend mit Verleihung des Jean-Servais-Stas-Preises und des Nachwuchspreises für Wissenschaftlerinnen und Wissenschaftler / Congress ceremony and dinner – Presentation of the 2015 laureate of the Jean-Servais-Stas award and of the winner of the GTFCh Young Scientists award

Festvortrag / Lecture
Prof. Dr. Dr. h.c. Hans H. Maurer (Homburg/Saar)
20 Mal Mosbach

23:00 Uhr    After Dinner Party (Hopfenkeller der Alten Mälzerei)

 

Samstag, 13. April 2019

9:00 Uhr    Vorträge: Hochauflösende Massenspektrometrie / Fallberichte / Freie Themen aus der Forensischen und toxikologischen Chemie /  Oral presentations: High resolution mass spectrometry / Case reports / Communications in forensic chemistry and toxicology

V22    Madeleine Pettersson Bergstrand, Markus R. Meyer, Olof Beck, Anders Helander, Stockholm (Schweden), Homburg/Saar
Human metabolic patterns of the designer benzodiazepines flubromazolam and pyrazolam studied by liquid chromatography-high resolution mass spectrometry

V23    Julia Dinger, Daniela Remane, Sylvia Morgenthal, Matthias Eppler, Gita Mall, Frank T. Peters, Jena
Three fatal intoxications involving the synthetic cannabinoid receptor agonist 5-F-ADB

V24    Sabrina Lehmann, Bastian Schulze, Thomas Kamphausen, Mario Thevis, Markus A. Rothschild, Katja Mercer-Chalmers-Bender, Köln 
Organ distribution of 4-MEC, MDPV, methoxetamine and α-PVP: comparison of QuEChERS and SPE

V25    Sandra N. Staeheli, Martina I. Boxler, Andrea Oestreich, Michelle Marti, Dominic Gascho, Stephan Bolliger, Thomas Kraemer, Andrea E. Steuer, Zürich (Schweiz)
Postmortem distribution and redistribution of new psychoactive substances in blood and alternative matrices – a case report involving MDAI and 2-MAPB 

V26    Konrad Sydow, Christopher Wiedfeld, Burkhard Madea, Frank Mußhoff, Bernd Stratmann, Cornelius Heß, Bonn, München, Bad Oeynhausen
Evaluation of a diabetic coma post mortem by analysis of 1,5-anhydroglucitol in urine

V27    Patrick Dahm, Katharina Janßen, Markus A. Rothschild, Katja Mercer-Chalmers-Bender, Köln
Fatal collapse during sex party involving amphetamines, poppers and other drugs

V28    Martin Jübner, Sabrina Lehmann, Justus Beike, Markus A. Rothschild, Katja Mercer-Chalmers-Bender, Köln
Pericardial fluid – appropriate alternative material for postmortal immunological screening analysis? 

V29        Marco Elmiger, Michael Poetzsch, Andrea E. Steuer, Thomas Kraemer, Zürich (Schweiz)
General unknown screening – Peak extraction and hit optimization using a design of experiment approach

V30    Andrea E. Steuer, Kim Arnold, Tom Schneider, Michael Poetzsch, Thomas Kraemer, Zürich (Schweiz)
A new metabolomics-based strategy for identification of endogenous markers of urine adulteration

10:40 Uhr     Kaffee-Pause / Coffee break
 

11:10 Uhr     Vorträge: Freie Themen aus der Forensischen Chemie und Toxikologie / Oral presentations: Communications in forensic chemistry and toxicology

V31    Saskia Penzel, Jessica Welter-Luedeke, Anna Zangl, Katrin Groß, Inge Herrle, Claudia Gutjahr-Ruhland, Matthias Graw, Liane D. Paul, München
A case series of α-pyrrolidinopentiothiophenone (α-PVT), a new psychoactive substance

V32    Florian Veit, Daniel Rentsch, Sonja Remacle, Freidoon Erdmann, Jost Beelitz, Walter Martz, Gießen, Rostock, Marburg
Determination of cyanide in porcine blood after experimental inhalation of combustion gases 

V33    Julian A. Michely, Hans H. Maurer, Homburg/Saar
Assessing the severity of acute poisonings – Is a multi-analyte one-point calibration LC-MS/MS approach accurate enough for estimation of drug levels?

V34    Oliver Lerch, Justus Beike, Hilke Andresen-Streichert, Tobias Kieliba, Münster, Köln
Automated GC-MS/MS determination of cannabinoids in hair with focus on THC-COOH and THC-OH

V35    Marianne Hädener, Stefan König, Marie Martin Fabritius, Wolfgang Weinmann, Bern (Schweiz)
Using THC-COOH cut-off concentrations for assessing cannabis consumption frequency: a recently detected THC-COOH isomer poses an important analytical problem

V36    Frank T. Peters, Daniela Remane, Gita Mall, Jena
Determination of ethyl glucuronide and ethyl sulfate in serum as a complement to congener analysis in cases of hip-flask defense?

V37    Reinhild Beyreiß, Stefanie Schröfel, Karsten Stemmerich, Torsten Arndt, Ingelheim
CEDIA Sample Check does not detect boric acid adulteration of ethyl glucuronide urines

V38    Lena-Maria Mehling, Thomas Piper, Susanne Lott, Josef Dib, Daniel Sejer Pedersen, Eva Sauer, Anna Heidbreder, Peter Young, Sys Stybe Johansen, Xin Wang, Annika Spottke, Burkhard Madea, Cornelius Courts, Mario Thevis, Cornelius Heß, Bonn, Köln, Kopenhagen (Dänemark), Kiel, Münster
Several possible toxicological and genetic tools for the extension of the detection window after GHB intake
 

12:50 Uhr    Schlusswort zum Symposium / Closing words

13:00 Uhr     Tagungsende / End of the meeting

 
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