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Postgraduate Professional Education Catalogue for Certification as “Clinical Toxicologist GTFCh“


Appendix 1 of Postgraduate Professional Education Regulations “Clinical Toxicologist GTFCh“


The applicant must acquire thorough specific knowledge, experience and skills in the area of clinical toxicology according to scientific and technical standards. Amongst others, the following is required
Independent planning and processing of clinical-toxicological analyses, reporting of results and providing expert opinions including clinical-toxicological consultation in light of the latest scientific advances
  • Publishing independent scientific papers in acknowledged journals
  • Participating in postgraduate professional education courses organised by the GTFCh
  • Participating in scientific meetings (workshops, conventions etc.)
The applicant may substantiate acquired knowledge, experience and skills by additional
  • Visits in other postgraduate professional education institutions
  • participation in postgraduate professional education courses arranged by other institutions related to clinical toxicology (associations, chambers)
  • conducting of own lectures and courses
  • successful participation in postgraduate university courses or seminars in related topics
The applicant needs postgraduate professional and continuing education in the areas (postgraduate professional education modules) listed below:

Postgraduate Professional Education Modules

Basics of human biology

Basic knowledge of the function of the human body (anatomy, physiology, biochemistry)


Pharmacodynamics and pharmacokinetics, pharmacogenetics

Structure of relevant medical substances and toxins, structure-response relationship, physical mechanism, spectrum of efficacy, adverse reaction, interaction, abuse and addiction potential, overdose symptoms, therapeutic measures, antidotes, xenobiotic metabolism, organ toxicology

Basics of general toxicology (acute and chronic toxicity, carcinogenicity, mutagenicity, reproduction toxicity)

Basics of pharmaceutical technology and biopharmacy

Clinical Toxicology

Epidemiology of acute poisonings

Pathophysiology and Pathobiochemistry of the most frequent types of poisoning

Differential diagnosis and cardinal symptoms of poisoning

Basic knowledge of emergency medical measures

Therapy of acute and chronic poisoning (primary and secondary toxin removal, antidotes etc.)

Basic knowledge in addiction therapy

Estimation of danger potential of hazardous substances and toxicological risk assessment

Clinical chemistry and laboratory medicine

Basics of biochemistry, clinical chemistry and pathobiochemistry

Effects of poisoning on clinical-chemical parameters

Evaluation of toxicologically relevant clinical-chemical parameters

Toxicological aspects of microbiology

Analytical toxicology


Standard matrices

Alternative matrices

Pre-analytical aspects

Sampling, transportation, and storage


Method development and validation

Qualitative and quantitative analysis procedures

Sample preparation (conjugate cleavage, extration and derivatisation procedures)

Separation techniques (e.g. gas chromatography, liquid chromatography)

Detection techniques (e.g. photometry, mass spectrometry, fluorescence spectrometry, atom absorption spectrometry)

Immuno-chemical procedures (including analytical assessment)

Quality assurance measures including internal and external quality control

Post analytics

Sample storage

Basics of bio statistics

Quality Management

Quality assurance measures



Clinical-toxicological assessment of findings, expert opinion and counselling

Plausibility control of clinical-toxicological analyses results
Interpretation of clinical-toxicological analyses results under consideration of the patient's clinical state and pharmaco-toxicological properties of the relevant substances
Clinical-toxicological consultation

Basics of forensic toxicology and forensic chemistry


Relevant laws and regulations

Medication law, narcotics law, chemical law, medical products law, crop protection law, foodstuffs law and commodities law

Duty to non-disclosure and data protection regulations

Legal aspects in diagnostics and treatment in cases of poisoning

Rights and duties of experts